Academic training

  1. Postdoc

    IOCB Prague and Baylor College of Medicine

    Advisors: Vaclav Veverka (structural biology), H. Courtney Hodges (genomics and live-cell imaging)

  2. PhD, Biomedical Sciences (Cancer program)

    KU Leuven, Leuven, Belgium

    Advisor: Zeger Debyser, chair of Molecular Medicine

  3. MSc, Biochemistry

    Charles University, Prague

    Advisor: Pavlina Rezacova

  4. BSc, Biochemistry

    Charles University, Prague

Grants, fellowships, and awards

  • Poster presentation award, MCB department research retreat, Houston, USA
  • Flash talk award, Dan L Duncan Comprehensive Cancer Center Annual Symposium, Houston, USA
  • Travel grant, European Molecular Biology Organization (EMBL/EMBO Meeting, The Nucleosome: From Atoms to Genomes, Heidelberg, Germany
  • Petr Sedmera award for outstanding work in NMR, Association of Czech NMR Spectroscopists (IMMSS)
  • Competitive grant for participation in a conference abroad, Flanders Research Foundation (FWO), Keystone Symposium, Epigenetics and Cancer, Keystone, CO, USA
  • Doctoral fellowship, Flanders Research Foundation (FWO), Belgium
  • Merit scholarship, Charles University, Prague, Czech Republic

Talks and oral presentations

  1. January 2023, Invited talk: Department of Structural Biology seminar series, St. Jude Children’s Research Hospital, Memphis, USA
    A disordered interaction module orchestrates transcription elongation.
  2. Nov. 2022, RNA and Chromatin seminar series, Baylor College of Medicine, Houston, USA
    Reactivation of the G1 enhancer landscape underlies SWI/SNF addiction.
  3. October 2022, EpiBio: International meeting on Epigenetics & Bioengeneering, Houston, USA
    Dynamic reactivation of the G1 enhancer landscape underlies SWI/SNF addiction.
  4. Sept. 2022, Cold Spring Harbor Meeting on Epigenetics & Chromatin, Cold Spring Harbor, USA
    A disordered interaction module orchestrates transcription elongation.
  5. Feb. 2022, Bert O’Malley "Overduckers" seminar series, Baylor College of Medicine, Houston, USA
    A ubiquitous disordered protein interaction module orchestrates transcription elongation.
  6. Sept. 2021, Dan L Duncan Comprehensive Cancer Center Annual Symposium, Baylor College of Medicine, Houston, USA
    Targeting SMARCA4 addiction in high-risk neuroblastoma.
  7. May 2021, RNA and Chromatin seminar series, Baylor College of Medicine, Houston, USA
    A ubiquitous disordered protein interaction module orchestrates transcription elongation.
  8. Sept. 2018, Postdoctoral association "Slice of science" series, Baylor College of Medicine, Houston, USA
    Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
  9. August 2017, EMBO/EMBL meeting, The Nucleosome: From Atoms to Genomes, Heidelberg, Germany
    Structural and functional characterization of LEDGF/p75 in complex with cellular and pathogenic binding partners.
  10. August 2017, EMBO/EMBL meeting, The Nucleosome: From Atoms to Genomes, Heidelberg, Germany
    Dominant-negative Smarca4 (Brg1) mutations induce convergent effects on the enhancer landscape.
  11. April 2017, Central European NMR Meeting, Valtice, Czech Republic
    Structural basis for overlap of LEDGF/p75 and HRP-2 in MLL Leukemia.
  12. May 2014, Oncoforum, Leuven, Belgium
    The LEDGF/p75-MLL complex as a new target for the treatment of MLL-dependent Leukemia.

We aim to tackle the most exciting problems in structural biology and gene regulation.